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  • Cutaneous histiocytosis is an uncommon condition in dogs. It is a non-cancerous increase in the number of reactive cells (histiocytes) caused by an immune system dysfunction. It generally manifests as multiple bumps and nodules confined to the dog's skin. The clinical signs, diagnosis, and treatment of this condition are explained in this handout.

  • Skin cancers are common in cats, but cutaneous lymphoma is relatively uncommon. Less than 2% of lymphoma cases in cats occur in the skin. As the disease progresses, the skin becomes thickened, reddened, ulcerated, and may ooze fluid. The most common locations to find lesions include the junction between mucus membranes and the skin. Unfortunately, feline cutaneous lymphoma is considered incurable. Surgical removal can be attempted for solitary lesions, although the tumor often returns to the area or will have spread elsewhere in the body already

  • Systemic lymphoma is a very common cancer in dogs, but the cutaneous form is quite rare. Current statistics suggest that cutaneous lymphoma accounts for only about 5% of canine lymphoma cases. The disease can present in a variety of lesions, including ulcers, nodules, red patches, and areas of hair loss and skin scaling. Because not very much is known about canine cutaneous lymphoma, there are no standard treatment protocols and the prognosis is poor.

  • Cuterebra are botflies that spend the larvae stage of their lifecycle within rodent or rabbit hosts and can accidentally infect dogs. They enter through the nose, mouth or a skin wound. They usually develop a cyst under the skin that can be located as it enlarges and often a breathing hole can be seen. The larva (warble) will leave the dog when it is ready to form a pupa but it will often leave behind a secondary bacterial skin infection or abscess in the empty cyst. Rarely, the larva/cuterebra migrate aberrantly through the dog causing inflammation and damage to different tissues, including the brain and eyes, and even potentially cause a severe systemic inflammatory response. Treatment depends on what damage has been done and can include removal of the warble, debridement or removal of the cyst, antibiotics and symptomatic and supportive treatment of the results of aberrant migration. Prognosis is generally good if only the skin is involved. Cuterebra infection can not be prevented easily, so monitoring the dog regularly for signs is important.

  • Cuterebra is the scientific name for the North American rabbit or rodent botfly. Cats are accidental hosts of Cuterebra larvae, and they are rarely evident from external skin inspection. A hole enlarges when the warble has matured, often leading to an infected empty cyst. Treatment depends on when the condition is discovered, and in many cases, antibiotics are used to treat secondary infections.

  • Blue-green algae, also called cyanobacteria, are found in fresh and brackish water of ponds and lakes. These microscopic bacteria can also grow in backyard fountains, garden pots, bird baths, and anywhere water is stagnant. Regardless of where they are found, cyanobacteria can be dangerous.

  • Cyanocobalamin (vitamin B12 or cobalamin) is a vitamin supplement used to treat systemic deficiencies. It can be given through a subcutaneous injection or oral tablet. The injection may sting temporarily, but otherwise is very safe. If a negative reaction occurs, call your veterinary office.

  • Cyanosis is a bluish discoloration of the skin and mucous membranes of the body caused by inadequate oxygen levels. Cyanosis is an emergency, and the root cause may be life-threatening and may or may not be reversible. Once back home, homecare instructions must be followed carefully.

  • Cyanosis is a bluish discoloration of the skin and mucous membranes of the body caused by inadequate oxygen levels. Cyanosis is an emergency, and the root cause may be life-threatening and may or may not be reversible. Once back home, homecare instructions must be followed carefully.

  • Cyclophosphamide is given by mouth or injection and is used off label to treat various cancers such as lymphoma, leukemia, carcinoma, and sarcoma. Common side effects include hair loss and hair coat changes. Do not use in pets that are allergic to it or that cannot be sufficiently monitored during treatment, are pregnant or lactating, have urinary obstruction, infection, bone marrow dysfunction, or have had an episode of blood in the urine that is not associated with a bladder infection. If a negative reaction occurs, please call your veterinary office.